Eosinophilic Gastrointestinal Disorders

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What are EGIDs?

Eosinophilic gastrointestinal disorders (EGIDs) are chronic digestive system disorders in which certain food proteins trigger an overproduction of eosinophils (white blood cells that help fight certain infections) in different areas of the digestive tract.

EGIDs typically fall into one of these types:

Eosinophilic esophagitis (EoE): esophagus

Eosinophilic gastritis (EoG): stomach

Eosinophilic enteritis (EoN): small bowel

  • Eosinophilic duodenitis (EoD): duodenum (first part of the small intestine)
  • Eosinophilic jejunitis (EoJ): jejunum (middle part of the small intestine)
  • Eosinophilic ileitis (EoI): ileum (last part of the small intestine)

Eosinophilic colitis (EoC): colon

Common symptoms of EGIDs:

  • Vomiting or nausea
  • Abdominal or chest pain
  • Acid reflux that does not respond to usual therapy
  • Bloating
  • Blood in the stool

How to manage EGIDs

Your doctor may be able to identify specific food proteins that trigger the overproduction of eosinophils in your child. Your doctor may recommend an elimination diet where the offending proteins are not consumed and may recommend supplementing with an amino acid-based formula.

Did You Know?

Studies have shown that hypoallergenic, amino acid-based formulas can help manage clinical symptoms of eosinophilic esophagitis (EoE).1,2

How EleCare® and EleCare® Jr may help

EleCare and EleCare Jr are nutritionally complete, hypoallergenic, amino acid-based formulas. Both support growth when used as the primary source of nutrition.3,4,* EleCare is clinically shown to significantly improve symptoms in infants and children with malabsorption issues and short bowel syndrome.5,* 

For more information about EGIDs, check out:

American Partnership for Eosinophilic Disorders

The APFED supports patients and their families with education, awareness, research, support and advocacy.

The Oley Foundation

The Oley Foundation gives people living with home intravenous nutrition and tube feeding the tools and confidence they need to achieve normalcy in their lives.

CURED Foundation

CURED is a non-profit foundation committed to raising substantial funding to aid in research, advocating on behalf of EGID patients and their families.

Kaareen’s Story

Learn how EleCare helped support the nutrition of a patient, and helped them get back to loving life.

Depending on your child's condition, some states may offer insurance coverage for elemental formulas. This varies from state to state and may not apply to all insurance plans. To check eligibility, contact your insurance plan or call Pathway Plus at 1-855-217-0698 for assistance.

Other Conditions

Food Allergies

Your child is not alone. In fact, it’s estimated that 4 out of every 100 children in the US have food allergies.6

Short Bowel Syndrome (SBS)

Short bowel syndrome describes a group of problems affecting individuals who have lost the use of a major part of their small intestine.

Malabsorption and Other Conditions

Malabsorption means that a child's body has trouble absorbing nutrients from food.

Food Protein-Induced Enterocolitis Syndrome (FPIES)

FPIES is a non-IgE-mediated food allergy. It's commonly characterized by profuse vomiting. 

References: 1. Liacouras CA, et al. Clin Gastroenterol Hepatol. 2005;3:1198-1206. 2. Furuta GT, et al. Gastroenterology. 2007;133:1342-1363. 3. Sicherer SH, et al. J Pediatr. 2001;138(5):688-693. 4. Borschel MW, et al. Clin Pediatr. 2013;52(10):910-917. 5. Borschel MW, et al. BMC Pediatrics. 2014;14:136. 6. Branum AM, Lukacs. Food allergy among US children: Trends in prevalence and hospitalizations. NCHS data brief, No. 10. Hyattsville, MD: National Center for Health Statistics. 2008. Centers for Disease Control and Prevention, National Center for Health Statistics website. http://www.cdc.gov/nchs/data/databriefs/db10.pdf. Published October 2008. Accessed March 20, 2024.